Different skin thinning potential of equipotent medium-strength glucocorticoids.

  title={Different skin thinning potential of equipotent medium-strength glucocorticoids.},
  author={Hans Christian Korting and Angela Unholzer and Monika Sch{\"a}fer-Korting and Irene Tausch and Johannes Gassmueller and K H Nietsch},
  journal={Skin pharmacology and applied skin physiology},
  volume={15 2},
In this study, we investigated the effect of prednicarbate, mometasone furoate and betamethasone 17-valerate on total skin thickness over a treatment period of 6 weeks. The study was conducted as a double-blind, placebo-controlled randomized clinical trial with a confirmatory approach. The influence of these drugs on healthy human skin under non-occlusive conditions was assessed by measuring total skin thickness and epidermal thickness using 20 and 50 MHz sonography, respectively. Epidermal… CONTINUE READING