Different responses of articular cartilage to strenuous running and joint immobilization.

@article{Ni2016DifferentRO,
  title={Different responses of articular cartilage to strenuous running and joint immobilization.},
  author={G X Ni and Yue-Zhu Zhou and Wei Chen and Lei Xu and Zhe Li and Sheng-Yao Liu and Lei Lei and Li-Qiong Zhan},
  journal={Connective tissue research},
  year={2016},
  volume={57 2},
  pages={143-51}
}
OBJECTIVE To compare the pathological changes in cartilage derived from rats that developed osteoarthritis either by joint immobilization or by strenuous treadmill running in order to better understand their respective pathomechanism. METHOD A total of 24 male Wistar rats were randomly assigned to three groups: sedentary control (CON), immobilization (IM), and strenuous running (SR). For rats in the IM group, unilateral knee joint was immobilized in flexion. Rats in the SR group underwent… CONTINUE READING
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