Different regulation of oestrogen receptors alpha and beta in the human cervix at term pregnancy.

@article{Wang2001DifferentRO,
  title={Different regulation of oestrogen receptors alpha and beta in the human cervix at term pregnancy.},
  author={Hong Bin Wang and Ylva Stjernholm and Gunvor Ekman and Hanna Eriksson and Lena Sahlin},
  journal={Molecular human reproduction},
  year={2001},
  volume={7 3},
  pages={293-300}
}
During pregnancy, a cervical connective tissue remodelling takes place, clinically recognized as softening, effacement and dilatation. The role of oestrogens and their receptors (ER) in this process is not clear. ERalpha is a ligand-activated transcription factor involved in many physiological processes. The identification of a second oestrogen receptor, ERbeta, has led to a re-evaluation of oestrogen signalling and physiology. The aim of this study was to monitor the expression of the two ERs… CONTINUE READING

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