Different patterns of calcium signaling triggered through two components of the B lymphocyte antigen receptor.

@article{Choquet1994DifferentPO,
  title={Different patterns of calcium signaling triggered through two components of the B lymphocyte antigen receptor.},
  author={Denis Choquet and G Ku and Sylvanie Cassard and Bernard Malissen and H Korn and Wolf Herman Fridman and Christian Bonnerot},
  journal={The Journal of biological chemistry},
  year={1994},
  volume={269 9},
  pages={6491-7}
}
The engagement of the B cell antigen receptor is the first step of antigenic stimulation of B lymphocytes. This step is followed by a series of biochemical events, including the activation of protein-tyrosine kinases, phosphoinositide turnover, and multiple patterns of calcium mobilization, which lead to the regulation of gene transcription and cellular responses. The B cell antigen receptor complex is composed of membrane immunoglobulins (as antigen recognition subunits) and associated chains… CONTINUE READING

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