Different patterns of autonomic nerve activity produced by a polar vs. a neutral cardiac glycoside.


Digitalis agents react with various peripheral reflex receptor areas (i.e., carotid artery baroreceptors and cardiac mechanoreceptors) to alter autonomic nerve activity. Physical characteristics of these reflex receptors differ and thus they may respond differently to polar and neutral cardenolides. Our purpose was to determine the effect of progressive i.v… (More)