Different pattern of T cell receptor δ gene rearrangement in tumour-infiltrating lymphocytes and peripheral blood in patients with solid tumours

@article{Kowalczyk1994DifferentPO,
  title={Different pattern of T cell receptor δ gene rearrangement in tumour-infiltrating lymphocytes and peripheral blood in patients with solid tumours},
  author={Driusz Kowalczyk and Witold Skorupski and Michal Drews and Jerzy Stanisław Nowak},
  journal={Cancer Immunology, Immunotherapy},
  year={1994},
  volume={39},
  pages={275-278}
}
Tumor-infiltrating lymphocytes (TIL) and peripheral blood lymphocytes (PBL) from four patients with renal-cell carcinoma (three paired with blood), two colon carcinomas (both paired with blood) and two melanomas (blood was not available) were analysed for the T cell receptor (TCR) δ gene repertoire. Polymerase chain reaction analysis, employing a panel of specific primers for TCR δ gene segments, showed different gene rearrangement patterns in TIL and PBL in all patients. Simultaneous analysis… CONTINUE READING

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