Different pathways are involved in arsenic-trioxide-induced cell proliferation and growth inhibition in human keratinocytes.

@article{Bi2010DifferentPA,
  title={Different pathways are involved in arsenic-trioxide-induced cell proliferation and growth inhibition in human keratinocytes.},
  author={Xin-ling Bi and Jianhua Gu and Zhanjun Guo and Si-feng Tao and Yuying Wang and Luo-sheng Tang and Jieqing Wu and Qiuwen Mi},
  journal={Skin pharmacology and physiology},
  year={2010},
  volume={23 2},
  pages={68-78}
}
BACKGROUND Arsenic is a carcinogen that is associated with an increased risk of human skin cancer. On the other hand, arsenic trioxide (As(2)O(3)) has potential anticancer activity against a wide range of carcinomas. The mechanisms involved in these two opposing processes remain unclear. METHODS We used normal human keratinocytes (NHK), the human keratinocyte HaCaT cell line and human epidermal carcinoma cells (A431 cell line) to investigate potential pathways involved in the effects on cell… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 28 references

Similar Papers

Loading similar papers…