Different pain, different brain: thalamic anatomy in neuropathic and non-neuropathic chronic pain syndromes.

@article{Gustin2011DifferentPD,
  title={Different pain, different brain: thalamic anatomy in neuropathic and non-neuropathic chronic pain syndromes.},
  author={S. M. Gustin and C. C. Peck and S. L. Wilcox and Paul G Nash and Greg M Murray and Luke A. Henderson},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2011},
  volume={31 16},
  pages={5956-64}
}
Trigeminal neuropathic pain (TNP) and temporomandibular disorders (TMD) are thought to have fundamentally different etiologies. It has been proposed that TNP arises through damage to, or pressure on, somatosensory afferents in the trigeminal nerve, whereas TMD results primarily from peripheral nociceptor activation. Because some reports suggest that neuropathic pain is associated with changes in brain anatomy, it is possible that TNP is maintained by changes in higher brain structures, whereas… CONTINUE READING
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