Different number of intravesical onabotulinumtoxinA injections for patients with refractory detrusor overactivity do not affect treatment outcome: A prospective randomized comparative study.

@article{Liao2016DifferentNO,
  title={Different number of intravesical onabotulinumtoxinA injections for patients with refractory detrusor overactivity do not affect treatment outcome: A prospective randomized comparative study.},
  author={Chun-Hou Liao and Sheng-Fu Chen and Hann-Chorng Kuo},
  journal={Neurourology and urodynamics},
  year={2016},
  volume={35 6},
  pages={717-23}
}
AIMS To examine the therapeutic effects and safety of different numbers of intravesical onabotulinumtoxinA (BoNT-A) injection for patients with detrusor overactivity (DO) refractory to antimuscarinics. METHODS Patients with DO, at least one daily episode of urgency or urgency incontinence refractory to previous antimuscarinics were randomly assigned to receive 10, 20, or 40 intravesical BoNT-A injections 100 U in 10 mL in the bladder body. Treatment results were assessed with global response… CONTINUE READING