Different molecular basis for spinal muscular atrophy in South African black patients.

@article{Stevens1999DifferentMB,
  title={Different molecular basis for spinal muscular atrophy in South African black patients.},
  author={Gwynn Stevens and T M Yawitch and J Rodda and S. Verhaart and Almut Krause},
  journal={American journal of medical genetics},
  year={1999},
  volume={86 5},
  pages={
          420-6
        }
}
  • Gwynn Stevens, T M Yawitch, +2 authors Almut Krause
  • Published in
    American journal of medical…
    1999
  • Medicine, Biology
  • Spinal muscular atrophy (SMA) is an autosomal recessive disorder occurring at a rate of between 1/5,000 and 1/10,000 births in most European countries. The phenotype results from the degeneration of the anterior horn cells of the spinal cord, resulting in symmetrical muscle weakness and wasting. The disorder can be classified according to the severity of the disease and the age of onset into three major types. Two candidate SMA genes, NAIP and SMN, isolated from the 5q13 region, have been… CONTINUE READING

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