Different modulation by live or killed Helicobacter pylori on cytokine production from peripheral blood mononuclear cells.

@article{Stassi2002DifferentMB,
  title={Different modulation by live or killed Helicobacter pylori on cytokine production from peripheral blood mononuclear cells.},
  author={Giorgio Stassi and Adriana Arena and Annalisa Speranza and Daniela Iannello and Pietro Mastroeni},
  journal={The new microbiologica},
  year={2002},
  volume={25 2},
  pages={247-52}
}
The mechanisms by which H. pylori colonizes and persists within the gastric mucosa are poorly understood. The induction and maintenance of gastric inflammation appear to depend on the complex interaction between a number of cytokines and chemokines. The gastric immune response observed "in vivo", during H. pylori infection, is characterized by a polarization of Th1 cell type that seems to be responsible for gastric pathology. The purpose of this study was to test the direct effect of H. pylori… CONTINUE READING

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