Different methylation and microRNA expression pattern in male and female familial breast cancer.

@article{Pinto2013DifferentMA,
  title={Different methylation and microRNA expression pattern in male and female familial breast cancer.},
  author={Rosamaria Pinto and Brunella Pilato and Laura Ottini and Rossana Lambo and Giovanni Simone and Angelo Virgilio Paradiso and Stefania Tommasi},
  journal={Journal of cellular physiology},
  year={2013},
  volume={228 6},
  pages={1264-9}
}
Epigenetic regulation, has been very scarcely explored in familial breast cancer (BC). In the present study RASSF1A and RAR beta promoter methylation and miR17, miR21, miR 124, and let-7a expression were investigated to highlight possible differences of epigenetic regulation between male and female familial BC, also in comparison with sporadic BC. These epigenetic alterations were studied in 56 familial BC patients (27 males and 29 females) and in 16 female sporadic cases. RASSF1A resulted more… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

Male breast cancer is not congruent with the female disease.

Critical reviews in oncology/hematology • 2016
View 4 Excerpts
Highly Influenced

A Case-Matched Gender Comparison Transcriptomic Screen Identifies eIF4E and eIF5 as Potential Prognostic Markers in Male Breast Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research • 2017
View 1 Excerpt

Role of BioResponse 3,3′-Diindolylmethane in the Treatment of Human Prostate Cancer: Clinical Experience

Medical principles and practice : international journal of the Kuwait University, Health Science Centre • 2016

References

Publications referenced by this paper.
Showing 1-10 of 37 references

Novel genetic variants in microRNA genes and familial breast cancer.

International journal of cancer • 2009
View 5 Excerpts
Highly Influenced

The epigenetics of breast cancer

J Jovanovic, JA Ronneberg, J Tost, V. Kristensen
Mol Oncol 4:242–254. • 2010
View 5 Excerpts
Highly Influenced

Epigenetic modifications in cancer.

Clinical genetics • 2012
View 1 Excerpt

Similar Papers

Loading similar papers…