Different metastatic potential of in vitro and in vivo lines selected from Lewis lung carcinoma: correlation with response to different bleomycin schedulings.


In vitro and in vivo variant cell lines selected from Lewis lung carcinoma are described. In vitro tumor lines are shown to differ in their metastatic potential, evaluated as lung colony-forming ability. Moreover, corresponding in vivo sublines, derived from intramuscular implant of cultured tumor cells, exhibit the same behavior for metastases formation as… (More)


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