Different metabotropic glutamate receptors play opposite roles in synaptic plasticity of the rat medial vestibular nuclei.

@article{Grassi2002DifferentMG,
  title={Different metabotropic glutamate receptors play opposite roles in synaptic plasticity of the rat medial vestibular nuclei.},
  author={Silvarosa Grassi and Adele Frondaroli and V E Pettorossi},
  journal={The Journal of physiology},
  year={2002},
  volume={543 Pt 3},
  pages={795-806}
}
In the medial vestibular nuclei (MVN) of rat brainstem slices, the role of group II and III metabotropic glutamate receptors (mGluRs) and of the subtypes of group I mGluRs: mGluR1, mGluR5, was investigated in basal synaptic transmission and in the induction and maintenance of long-term potentiation (LTP). We used selective antagonists and agonists for mGluRs and we analysed the field potentials evoked by vestibular afferent stimulation before and after high-frequency stimulation (HFS) to induce… CONTINUE READING
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