Different measures of “genome-wide” DNA methylation exhibit unique properties in placental and somatic tissues

@inproceedings{Price2012DifferentMO,
  title={Different measures of “genome-wide” DNA methylation exhibit unique properties in placental and somatic tissues},
  author={E. Magda Price and Allison M. Cotton and Mar{\'i}a Serena Pe{\~n}aherrera and Deborah E. McFadden and Michael S. Kobor and Wendy P. Robinson},
  booktitle={Epigenetics},
  year={2012}
}
DNA methylation of CpGs located in two types of repetitive elements-LINE1 (L1) and Alu-is used to assess "global" changes in DNA methylation in studies of human disease and environmental exposure. L1 and Alu contribute close to 30% of all base pairs in the human genome and transposition of repetitive elements is repressed through DNA methylation. Few studies have investigated whether repetitive element DNA methylation is associated with DNA methylation at other genomic regions, or the… CONTINUE READING
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Analysis of repetitive element DNA methylation by MethyLight

Nucleic acids research • 2005
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