Different gene sets contribute to different symptom dimensions of depression and anxiety.

@article{Veen2012DifferentGS,
  title={Different gene sets contribute to different symptom dimensions of depression and anxiety.},
  author={Tineke van Veen and Jelle J. Goeman and Ramin Monajemi and Klaas J. Wardenaar and Catharina Annette Hartman and Harold Snieder and Ilja M. Nolte and Brenda W J H Penninx and Frans G Zitman},
  journal={American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics},
  year={2012},
  volume={159B 5},
  pages={519-28}
}
Although many genetic association studies have been carried out, it remains unclear which genes contribute to depression. This may be due to heterogeneity of the DSM-IV category of depression. Specific symptom-dimensions provide a more homogenous phenotype. Furthermore, as effects of individual genes are small, analysis of genetic data at the pathway-level… CONTINUE READING