Different functions of HetR, a master regulator of heterocyst differentiation in Anabaena sp. PCC 7120, can be separated by mutation.

@article{Khudyakov2004DifferentFO,
  title={Different functions of HetR, a master regulator of heterocyst differentiation in Anabaena sp. PCC 7120, can be separated by mutation.},
  author={Ivan Ya Khudyakov and James W. Golden},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2004},
  volume={101 45},
  pages={
          16040-5
        }
}
The HetR protein has long been recognized as a key player in the regulation of heterocyst development. HetR is known to possess autoproteolytic and DNA-binding activities. During a search for mutants of Anabaena sp. PCC 7120 that can overcome heterocyst suppression caused by overexpression of the patS gene, which encodes a negative regulator of differentiation, a bypass mutant strain, S2-45, was isolated that produced a defective pattern (Pat phenotype) of irregularly spaced single and multiple… CONTINUE READING

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