Different functional effect of Ro 15-4513 and Ro 19-4603 on synaptic responses of Purkinje cells in the rat cerebellar slice.


Modulation of GABA-mediated neurotransmissions by Ro 15-4513 in cerebellar slices was assessed following stimulation of the parallel fibre input, which, in this preparation, preferentially activates the inhibitory interneurones innervating Purkinje cells. Peristimulus-time histogram analysis of inhibitory responses of spontaneously-active Purkinje cells… (More)


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