Different events involved in the induction of macrophage tumor necrosis factor by Candida albicans and lipopolysaccharide.

@article{Blasi1994DifferentEI,
  title={Different events involved in the induction of macrophage tumor necrosis factor by Candida albicans and lipopolysaccharide.},
  author={Elisabetta Blasi and Lucia Pitzurra and Manuela Puliti and Rosanna Mazzolla and Roberta Barluzzi and Silvia Saleppico and Francesco Bistoni},
  journal={Cellular immunology},
  year={1994},
  volume={157 2},
  pages={
          501-9
        }
}
Using an in vitro experimental model, we have recently demonstrated that Candida albicans in its hyphal form (H-Candida), similarly to lipopolysaccharide (LPS), enhances tumor necrosis factor (TNF) secretory response in the cloned macrophage (M phi) population ANA-1. Here we show that H-Candida and LPS each differ in their requirements for intact protein kinase functions, susceptibility to 0.4-microns micropore-size membranes, and sensitivity to polymyxin B. These results, together with the… CONTINUE READING
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