Different effects of zolpidem and diazepam on hippocampal sharp wave-ripple activity in vitro.

@article{Koniaris2011DifferentEO,
  title={Different effects of zolpidem and diazepam on hippocampal sharp wave-ripple activity in vitro.},
  author={Efthymios Koniaris and Panagiota Drimala and Evangelos Sotiriou and Costas Papatheodoropoulos},
  journal={Neuroscience},
  year={2011},
  volume={175},
  pages={224-34}
}
Sharp waves and the concurrent high-frequency "ripple" oscillation (100-200 Hz) is a prominent intrinsic hippocampal network activity that occurs during slow-wave sleep and resting wakefulness with an important role in memory processes. Present data suggest that the generation of sharp wave-ripple (SWRs) requires a complex interaction between the various components of the hippocampal network with the important involvement of GABA(A) receptor (GABA(A)R)-mediated transmission. The positive… CONTINUE READING