Different effects of bisphosphonate and estrogen therapy on free and peptide-bound bone cross-links excretion.

@article{Garnero1995DifferentEO,
  title={Different effects of bisphosphonate and estrogen therapy on free and peptide-bound bone cross-links excretion.},
  author={Patrick Garnero and Evelyne Gineyts and P Arbault and Claus Christiansen and Pierre Dominique Delmas},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={1995},
  volume={10 4},
  pages={641-9}
}
We have measured the free and peptide-bound type I collagen cross-link excretions in normal women and in patients with metabolic bone disease using the HPLC technique and immunoassays recognizing specifically the free or peptide-bound forms of pyridinoline (Pyr). After menopause, free deoxypyridinoline (free D-Pyr) excretion measured by HPLC without urine… CONTINUE READING