Different effects of Bifeprunox, Aripiprazole, and Haloperidol on body weight gain, food and water intake, and locomotor activity in rats

@article{Santis2014DifferentEO,
  title={Different effects of Bifeprunox, Aripiprazole, and Haloperidol on body weight gain, food and water intake, and locomotor activity in rats},
  author={Michael De Santis and Bo Pan and Jiamei Lian and Xu-Feng Huang and Chao Deng},
  journal={Pharmacology Biochemistry and Behavior},
  year={2014},
  volume={124},
  pages={167-173}
}
Following on the success of Aripiprazole with its high clinical efficacy and minimal side effects, further antipsychotic drugs (such as Bifeprunox) have been developed based on the same dopamine D2 partial agonist pharmacological profile as Aripiprazole. However clinical trials of Bifeprunox have found differing results to that of its predecessor, without the same significant clinical efficacy. This study has therefore investigated the different effects of 10 week treatment with Aripiprazole (0… CONTINUE READING

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1 Excerpt

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