Different contribution of rat liver microsomal pigments in the formation of superoxide anions and hydrogen peroxide during development.

@article{Bartoli1977DifferentCO,
  title={Different contribution of rat liver microsomal pigments in the formation of superoxide anions and hydrogen peroxide during development.},
  author={Gianna Maria Bartoli and Tommaso Galeotti and G Palombini and Giovanni Parisi and Angelo Azzi},
  journal={Archives of biochemistry and biophysics},
  year={1977},
  volume={184 1},
  pages={
          276-81
        }
}
Abstract Liver microsomes of adult rats produce, by an NADPH-dependent pathway, O 2 − radicals, as detected by the epinephrine cooxidation to adrenochrome (24.8 nmol/min/mg of protein). This production has also been measured during liver development (from 1 to 20 days after birth) and correlated to the enzyme content (NADPH-cytochrome c reductase, cytochrome b 5 , and cytochrome P -450), with the aim of establishing the level at which Superoxide radicals are formed in the electron transport… CONTINUE READING