Different channel-gating properties of two classes of cyclic GMP-activated channel in vertebrate photoreceptors.

@article{Torre1992DifferentCP,
  title={Different channel-gating properties of two classes of cyclic GMP-activated channel in vertebrate photoreceptors.},
  author={Vincent Torre and Marco Straforini and Federico Sesti and T. D. Lamb},
  journal={Proceedings. Biological sciences},
  year={1992},
  volume={250 1329},
  pages={209-15}
}
We report that two types of cGMP-activated channel coexist in the photoreceptor plasma membrane, with the most commonly encountered class appearing broadly similar to the channel reported in previous patch-pipette experiments. However, we find that flickering of this channel between the open and closed states is so rapid that a discrete single-channel conductance cannot unequivocally be resolved; the occurrence of flickering is largely independent of membrane voltage and of the presence of… CONTINUE READING

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