Different alpha-adrenoreceptors in the central nervous system mediating biochemical and functional effects of clonidine and receptor blocking agents

@article{Andn1976DifferentAI,
  title={Different alpha-adrenoreceptors in the central nervous system mediating biochemical and functional effects of clonidine and receptor blocking agents},
  author={Nils-Erik And{\'e}n and Maria Grabowska and Ulf Str{\"o}mbom},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={1976},
  volume={292},
  pages={43-52}
}
SummaryThe influence of clonidine on α-adrenoreceptors in the central nervous system of rats and mice has been investigated. Both functional events due to postsynaptic receptor stimulation (flexor reflex activity, motor activity) and biochemical changes have been considered.1.Clonidine was less potent in stimulating the hindlimb flexor reflex activity of spinal rats than in inhibiting the α-methyltyrosine-induced disappearance of noradrenaline in the spinal cord and in the whole brain of rats.2… CONTINUE READING

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A History of Naunyn-Schmiedeberg’s Archives of Pharmacology

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