Different Implications of Paternal and Maternal Atopy for Perinatal IgE Production and Asthma Development

@inproceedings{Wu2012DifferentIO,
  title={Different Implications of Paternal and Maternal Atopy for Perinatal IgE Production and Asthma Development},
  author={Chih-Chiang Wu and Rong-fu Chen and Ho-Chang Kuo},
  booktitle={Clinical & developmental immunology},
  year={2012}
}
Asthma is a hereditary disease associated with IgE-mediated reaction. Whether maternal atopy and paternal atopy have different impacts on perinatal IgE production and asthma development remains unclear. This paper reviews and summarizes the effects of maternal and paternal atopy on the developmental aspects of IgE production and asthma. Maternal atopy affects both pre- and postnatal IgE production, whereas paternal atopy mainly affects the latter. Maternally transmitted genes GSTP1 and FceRI… CONTINUE READING
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