Differences in verotoxin neutralizing activity of therapeutic immunoglobulins and sera from healthy controls

@article{Bitzan1993DifferencesIV,
  title={Differences in verotoxin neutralizing activity of therapeutic immunoglobulins and sera from healthy controls},
  author={Dr. med. M. Bitzan and Dr. med. M. Klemt and cand. med. R. Steffens and Prof. Dr. D. E. M{\"u}ller-Wiefel},
  journal={Infection},
  year={1993},
  volume={21},
  pages={140-145}
}
Intestinal infection byEscherichia coli O157 and other verotoxin (VT) producingE. coli has been increasingly recognized as an important factor for the causation of classic (enteropathic) hemolytic uremic syndrome (HUS) and hemorrhagic colitis (HC). Toxins most frequently involved are VT1 and VT2. As with other toxin-mediated diseases, administration of immunoglobulin (Ig) may be beneficial. However, little is known about the immune response elicited by the toxin(s), and the prevalence of VT… CONTINUE READING
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