Differences in thermotolerance induced by heat or sodium arsenite: cell killing and inhibition of protein synthesis.

@article{Lee1990DifferencesIT,
  title={Differences in thermotolerance induced by heat or sodium arsenite: cell killing and inhibition of protein synthesis.},
  author={Young Jun Lee and L Perlaky and William C. Dewey and Elwood P. Armour and Peter M. Corry},
  journal={Radiation research},
  year={1990},
  volume={121 3},
  pages={295-303}
}
Chinese hamster ovary (CHO) cells became thermotolerant after treatment with either heat for 10 min at 45.5 degrees C or incubation in 100 microM sodium arsenite for 1 h at 37 degrees C. Thermotolerance was tested using heat treatment at 45 degrees C or 43 degrees C administered 6-12 h after the inducing agent. At 45 degrees C thermotolerance ratios at 10(-2) isosurvival levels were 4.2 and 3.8 for heat and sodium arsenite, respectively. Recovery from heat damage as measured by resumption of… CONTINUE READING