Differences in the recognition by CTL of peptides presented by the HLA-B*4402 and the HLA-B*4403 molecules which differ by a single amino acid.

Abstract

The HLA-B*4402 and B*4403 molecules differ only at residue 156, which borders the peptide binding site. Strong in vivo allogeneic reactions mediated by cytolytic T lymphocytes (CTLs) were reported in patients who received a bone marrow graft mismatched for these B44 subtypes, indicating that HLA-B*4402 and B*4403 molecules present distinct antigens. This… (More)

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Cite this paper

@article{Herman1999DifferencesIT, title={Differences in the recognition by CTL of peptides presented by the HLA-B*4402 and the HLA-B*4403 molecules which differ by a single amino acid.}, author={Joseph Herman and Victor Jongeneel and D. V. Kuznetsov and Pierre G Coulie}, journal={Tissue antigens}, year={1999}, volume={53 2}, pages={111-21} }