Differences in the kinetics of DNA repair in cancer patients and healthy controls.

@article{Kovacs1991DifferencesIT,
  title={Differences in the kinetics of DNA repair in cancer patients and healthy controls.},
  author={Eva Kovacs and Helen Langemann},
  journal={Oncology},
  year={1991},
  volume={48 4},
  pages={312-6}
}
The time course of DNA repair, using (3H)thymidine uptake as parameter, was measured during 8 h after a single exposure to 2, 8, and 16 UV-C J/m2 in lymphocytes of 8 cancer patients, 1 xeroderma pigmentosum patient and 10 controls. All patients had reduced repair, and all controls normal repair, as calculated 2 h after a single exposure. Six patients reached normal levels with a delay of 2-6 h, whereas 2 patients and the xeroderma pigmentosum patient did not. Although the kinetic curves in… CONTINUE READING