Differences in the incorporation of bromodeoxyuridine by human lymphoblastoid cell lines.

@article{Henderson1975DifferencesIT,
  title={Differences in the incorporation of bromodeoxyuridine by human lymphoblastoid cell lines.},
  author={Earl E. Henderson and Bernard S Strauss},
  journal={Cell},
  year={1975},
  volume={5 4},
  pages={381-7}
}
Long term human lymphoblastoid lines differ in their ability to grow in medium containing bromodeoxyuridine (BrdU) and to incorporate analog into their DNA. Eight Burkitt's lymphoma cell lines divided at least twice in BrdU-containing medium and made DNA in which over 90% of the thymidine residues were substituted with analog in both strands. Three infectious mononucleosis-derived lines and 24 lines transformed in vitro were inhibited by BrdU after one cell division and made only hybrid DNA in… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.