Differences in the expression pattern of apoptosis-related molecules between childhood and adult de novo acute myeloid leukemia.

@article{Wuchter2004DifferencesIT,
  title={Differences in the expression pattern of apoptosis-related molecules between childhood and adult de novo acute myeloid leukemia.},
  author={Christian Wuchter and Stephan Richter and Doreen Oltersdorf and Leonid Karawajew and W G Ludwig and Ingo Tamm},
  journal={Haematologica},
  year={2004},
  volume={89 3},
  pages={363-4}
}
Distinct expression patterns of pro- and anti-apoptotic proteins may contribute to different prognoses and therapy outcomes in adult versus childhood acute myeloid leukemia (AML). Therefore, we investigated whether expression levels of apoptosis-related proteins CD95, Bcl-2, Bax, Bcl-xL, procaspase-3, XIAP, cIAP-1, and survivin differ between children and adults with de novo AML.