Differences in the expression pattern of apoptosis-related molecules between childhood and adult de novo acute myeloid leukemia.

Abstract

Distinct expression patterns of pro- and anti-apoptotic proteins may contribute to different prognoses and therapy outcomes in adult versus childhood acute myeloid leukemia (AML). Therefore, we investigated whether expression levels of apoptosis-related proteins CD95, Bcl-2, Bax, Bcl-xL, procaspase-3, XIAP, cIAP-1, and survivin differ between children and adults with de novo AML.

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@article{Wuchter2004DifferencesIT, title={Differences in the expression pattern of apoptosis-related molecules between childhood and adult de novo acute myeloid leukemia.}, author={Christian Wuchter and Stephan Richter and Doreen Oltersdorf and Leonid Karawajew and W M Ludwig and Ingo Tamm}, journal={Haematologica}, year={2004}, volume={89 3}, pages={363-4} }