Differences in the chronic hypotensive mechanism of action of ketanserin in spontaneously hypertensive and Wistar-Kyoto rats.

Abstract

OBJECTIVE To investigate the hypotensive effect and mechanism of action of chronic administration of ketanserin in spontaneously hypertensive rats (SHR) and in normotensive Wistar-Kyoto (WKY) rats. METHODS AND RESULTS SHR and WKY rats were given chronic ketanserin infusions via osmotic minipumps to minimize fluctuations in drug concentrations and receptor… (More)

Topics

Cite this paper

@article{Balasubramaniam1994DifferencesIT, title={Differences in the chronic hypotensive mechanism of action of ketanserin in spontaneously hypertensive and Wistar-Kyoto rats.}, author={Govini Balasubramaniam and H. S. Lee and Sylvia Mah}, journal={Journal of hypertension}, year={1994}, volume={12 1}, pages={7-14} }