Differences in the chemical reactivity of individual molecules of an enzyme

@article{Xue1995DifferencesIT,
  title={Differences in the chemical reactivity of individual molecules of an enzyme},
  author={Qifeng Xue and Edward S. Yeung},
  journal={Nature},
  year={1995},
  volume={373},
  pages={681-683}
}
MUCH attention has been focused recently on the detection and physical characterization of individual molecules1–11. Using such methods to study the chemical properties, such as reactivity, of single molecules offers the potential to investigate how these might vary from molecule to molecule, and for individual molecules as a function of time. The complex structures of biomolecules such as enzymes make them particularly attractive targets for studying how subtle changes or differences at the… CONTINUE READING

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