Differences in renal metabolism of insulin and cytochrome c.

Abstract

Kidneys degrade small proteins such as cytochrome c (CYT c) by the classic lysosomal pathway. However, because alternate routes for the transport and degradation of protein hormones have been identified in other tissues, we set out to determine whether extralysosomal sites might participate in the renal degradation of insulin. First, we compared the effect… (More)

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Cite this paper

@article{Herrman1988DifferencesIR, title={Differences in renal metabolism of insulin and cytochrome c.}, author={J. Herrman and R. E. Simmons and Bernhard Frank and Richard Rabkin}, journal={The American journal of physiology}, year={1988}, volume={254 4 Pt 1}, pages={E419-28} }