Differences in gut microbial metabolism are responsible for reduced hippurate synthesis in Crohn's disease

Abstract

BACKGROUND Certain urinary metabolites are the product of gut microbial or mammalian metabolism; others, such as hippurate, are mammalian-microbial 'co-metabolites'. It has previously been observed that Crohn's disease (CD) patients excrete significantly less hippurate than controls. There are two stages in the biosynthesis of this metabolite: 1) gut… (More)
DOI: 10.1186/1471-230X-10-108

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@inproceedings{Williams2010DifferencesIG, title={Differences in gut microbial metabolism are responsible for reduced hippurate synthesis in Crohn's disease}, author={Horace R. T. Williams and Isobel J Cox and David G. Walker and Jeremy F. L. Cobbold and S. D. Taylor-Robinson and Sara E F Marshall and Timothy R. Orchard}, booktitle={BMC gastroenterology}, year={2010} }