Differences in gene expression and cytokine production by crystalline vs. amorphous silica in human lung epithelial cells


Exposure to respirable crystalline silica particles, as opposed to amorphous silica, is associated with lung inflammation, pulmonary fibrosis (silicosis), and potentially with lung cancer. We used Affymetrix/GeneSifter microarray analysis to determine whether gene expression profiles differed in a human bronchial epithelial cell line (BEAS 2B) exposed to… (More)
DOI: 10.1186/1743-8977-9-6


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