Differences in food intake of tumour-bearing cachectic mice are associated with hypothalamic serotonin signalling

@inproceedings{Dwarkasing2015DifferencesIF,
  title={Differences in food intake of tumour-bearing cachectic mice are associated with hypothalamic serotonin signalling},
  author={Jvalini T. Dwarkasing and Mark V. Boekschoten and Joseph M Argil{\'e}s and Miriam van Dijk and S{\'i}lvia Busquets and Fabio Penna and M{\'i}riam Toledo and Alessandro Laviano and Renger F. Witkamp and Klaske van Norren},
  booktitle={Journal of cachexia, sarcopenia and muscle},
  year={2015}
}
BACKGROUND Anorexia is a common symptom among cancer patients and contributes to malnutrition and strongly impinges on quality of life. Cancer-induced anorexia is thought to be caused by an inability of food intake-regulating systems in the hypothalamus to respond adequately to negative energy balance during tumour growth. Here, we show that this impaired response of food-intake control is likely to be mediated by altered serotonin signalling and by failure in post-transcriptional neuropeptide… CONTINUE READING