Differences in effects on drug absorption between dihydroxy and trihydroxy bile salts.

Abstract

The effect of a dihydroxy bile salt, sodium taurodeoxycholate (STDC), on drug absorption from rat small intestine was investigated in comparison with that of trihydroxy one, sodium cholate (STC). The enhancement or inhibitory effects on the absorption of various model drugs by STDC bore similar tendency to those by STC, and the magnitude was greater than… (More)

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Cite this paper

@article{Kimura1985DifferencesIE, title={Differences in effects on drug absorption between dihydroxy and trihydroxy bile salts.}, author={T. Kimura and Ken-ichi Inui and Hitoshi Sezaki}, journal={Journal of pharmacobio-dynamics}, year={1985}, volume={8 7}, pages={578-85} }