Differences in brain responses to visceral pain between patients with irritable bowel syndrome and ulcerative colitis.

@article{Mayer2005DifferencesIB,
  title={Differences in brain responses to visceral pain between patients with irritable bowel syndrome and ulcerative colitis.},
  author={Emeran A. Mayer and Steven M. Berman and Brandall Y. Suyenobu and Jennifer S. Labus and Mark A. Mandelkern and Bruce D. Naliboff and Lin Chang},
  journal={Pain},
  year={2005},
  volume={115 3},
  pages={398-409}
}
Patients with mild chronic inflammation of the rectum or ileum have reduced perceptual responses to rectosigmoid distension compared to patients with irritable bowel syndrome (IBS). The current study sought to identify differences in regional cerebral blood flow (rCBF) during rectal distension, which might correspond to these perceptual differences. In 8 male ulcerative colitis (UC) patients with quiescent disease, 7 male IBS patients and 7 healthy male controls, rCBF was assessed using 15O… CONTINUE READING
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