Differences in amino acids composition and coupling patterns between mesophilic and thermophilic proteins

@article{Zhou2007DifferencesIA,
  title={Differences in amino acids composition and coupling patterns between mesophilic and thermophilic proteins},
  author={X.-X. Zhou and Y. Wang and Y.-J. Pan and W.-F. Li},
  journal={Amino Acids},
  year={2007},
  volume={34},
  pages={25-33}
}
Thermophilic proteins show substantially higher intrinsic thermal stability than their mesophilic counterparts. Amino acid composition is believed to alter the intrinsic stability of proteins. Several investigations and mutagenesis experiment have been carried out to understand the amino acid composition for the thermostability of proteins. This review presents some generalized features of amino acid composition found in thermophilic proteins, including an increase in residue hydrophobicity, a… CONTINUE READING