Differences in T-helper polarizing capability between human monocyte-derived dendritic cells and monocyte-derived Langerhans'-like cells.

@article{Rajkovic2011DifferencesIT,
  title={Differences in T-helper polarizing capability between human monocyte-derived dendritic cells and monocyte-derived Langerhans'-like cells.},
  author={Ivan Rajkovic and Ana Dragicevi{\'c} and Sa{\vs}a Vasiliji{\'c} and Biljana D J Bo{\vz}i{\'c} and Tanja D{\vz}opali{\'c} and Sergej Tomi{\'c} and Ivana Majstorovi{\'c} and Dragana Bozidar Vucevic and Jelena Djoki{\'c} and Bela Balint and Miodrag {\vC}oli{\'c}},
  journal={Immunology},
  year={2011},
  volume={132 2},
  pages={217-25}
}
Langerhans' cells (LCs) represent a specific subset of dendritic cells (DCs) which are important for detecting and processing pathogens that penetrate the skin and epithelial barriers. The aim of our study was to explain what makes their in vitro counterparts - monocyte-derived Langerhans'-like cells (MoLCs) - unique compared with monocyte-derived dendritic cells (MoDCs). Immature MoDCs were generated by incubating peripheral blood monocytes with granulocyte-macrophage colony-stimulating factor… CONTINUE READING
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