Differences in Mouse Maternal Care Behavior – Is There a Genetic Impact of the Glucocorticoid Receptor?

@inproceedings{Chourbaji2011DifferencesIM,
  title={Differences in Mouse Maternal Care Behavior – Is There a Genetic Impact of the Glucocorticoid Receptor?},
  author={Sabine Chourbaji and Carolin Hoyer and Sophie Helene Richter and Christiane Brandwein and Natascha Pfeiffer and Miriam Annika Vogt and Barbara Vollmayr and Peter Gass},
  booktitle={PloS one},
  year={2011}
}
Depressive episodes are frequently preceded by stressful life events. Evidence from genetic association studies suggests a role for the glucocorticoid receptor (GR), an essential element in the regulation of stress responses, in the pathophysiology of the disorder. Since the stress response system is affected by pregnancy and postpartum-associated changes, it has also been implicated in the pathophysiology of postpartum depression. Using a 2 × 2 factorial design, we investigated whether a… CONTINUE READING

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