Differences in MAP kinase phosphorylation in response to mechanical strain in asthmatic fibroblasts

BACKGROUND Mechanical strain alters protein expression. It results in phosphorylation of MAP kinases and up-regulation of extracellular matrix proteins. We investigated whether phosphorylation of MAP kinase family members was increased in response to mechanical strain in fibroblasts from asthmatic patients (AF) and normal controls (NF), and whether… CONTINUE READING