Differences between the catalytic properties of recombinant human PC2 and endogenous rat PC2.

Abstract

Human prohormone convertase PC2 was expressed in Xenopus oocytes and its properties were compared with those of the Type-2 endopeptidase of rat insulin secretory granules, previously identified as PC2 [Bennett, Bailyes, Nielson, Guest, Rutherford, Arden and Hutton (1992) J. Biol. Chem. 267, 15229-15236]. Recombinant PC2 had the same substrate specificity as… (More)

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@article{Bailyes1995DifferencesBT, title={Differences between the catalytic properties of recombinant human PC2 and endogenous rat PC2.}, author={E. M. Bailyes and Kathleen I J Shennan and Elena F. Usac and Susan D. Arden and Paul c. Guest and Kenneth S. Docherty and John C. Hutton}, journal={The Biochemical journal}, year={1995}, volume={309 ( Pt 2)}, pages={587-94} }