Differences between prescribed daily doses and defined daily doses of antiepileptics--therapeutic drug monitoring as a marker of the quality of the treatment.

@article{Koristkova2006DifferencesBP,
  title={Differences between prescribed daily doses and defined daily doses of antiepileptics--therapeutic drug monitoring as a marker of the quality of the treatment.},
  author={Blanka Koristkova and Milan Grundmann and Hana Brozmanova},
  journal={International journal of clinical pharmacology and therapeutics},
  year={2006},
  volume={44 9},
  pages={
          438-42
        }
}
OBJECTIVE Prescribed daily doses (PDDs) of antiepileptics (N03A ATC group) were recorded for drugs used in monotherapy or in combination therapy in the University Hospital in Ostrava, Czechia. Plasma levels were used as an indicator of the quality of treatment. METHOD Request and reply forms for therapeutic drug monitoring (TDM) were used as a source of PDDs and plasma levels. The study included 1,144 in-patients examined in the period 1993 - 2004. The differences in PDD were tested by Mann… Expand
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