Differences between mouse and rat myocardial contractile responsiveness to calcium.

@article{Brooks1999DifferencesBM,
  title={Differences between mouse and rat myocardial contractile responsiveness to calcium.},
  author={W. Douglas Brooks and Chester Conrad},
  journal={Comparative biochemistry and physiology. Part A, Molecular & integrative physiology},
  year={1999},
  volume={124 2},
  pages={139-47}
}
Genetically altered mice have become an increasingly important tool for the study of mechanisms of cardiac function, and therefore it is vital to characterize the basic contractile properties of the mouse heart. As a first approach to this goal, we first optimized perfusion conditions and characterized the effect of incremental left ventricular balloon inflation on end-diastolic, systolic and developed pressures in the isovolumically-contracting mouse heart. Under constant loading conditions… CONTINUE READING