Differences between karyotypically normal and abnormal human embryonic stem cells.

@article{Yang2010DifferencesBK,
  title={Differences between karyotypically normal and abnormal human embryonic stem cells.},
  author={Sheng Yang and Ge Lin and Yue-Qiu Tan and L Deng and Ding Yuan and G-X Lu},
  journal={Cell proliferation},
  year={2010},
  volume={43 3},
  pages={195-206}
}
OBJECTIVES To compare different biological characteristics of human embryonic stem cells (HESCs) between those with normal and those with abnormal karyotype. MATERIALS AND METHODS Culture-adapted HESCs (chHES-3) with abnormal karyotype were compared with karyotypically normal cells, with regard to pluripotency and differentiation capacity, ultrastructure, growth characteristics, gene expression profiles and signalling pathways. RESULTS We found a new abnormal karyotype of HESCs. We observed… CONTINUE READING
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