Differences and the Relationship in Default Mode Network Intrinsic Activity and Functional Connectivity in Mild Alzheimer's Disease and Amnestic Mild Cognitive Impairment

@article{Weiler2014DifferencesAT,
  title={Differences and the Relationship in Default Mode Network Intrinsic Activity and Functional Connectivity in Mild Alzheimer's Disease and Amnestic Mild Cognitive Impairment},
  author={Marina Weiler and Camila Vieira Ligo Teixeira and Mateus Henrique Nogueira and Brunno Machado de Campos and Benito Pereira Damasceno and Fernando Cendes and Marcio Luiz Figueredo Balthazar},
  journal={Brain connectivity},
  year={2014},
  volume={4 8},
  pages={567-74}
}
There is evidence that the default mode network (DMN) functional connectivity is impaired in Alzheimer's disease (AD) and few studies also reported a decrease in DMN intrinsic activity, measured by the amplitude of low-frequency fluctuations (ALFFs). In this study, we analyzed the relationship between DMN intrinsic activity and functional connectivity, as well as their possible implications on cognition in patients with mild AD and amnestic mild cognitive impairment (aMCI) and healthy controls… CONTINUE READING

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